Адамантиламин

[Karamba]

Скажите пожалуйста насколько опасен (токсичен) адамантил амин

 

[paveltashkinov]

Гугл в помощь.

 

Deaths have been reported from overdose with amantadine. The lowest reported acute lethal dose was 2 grams.

 

 

Amantadine has been associated with several central nervous system (CNS) side effects, likely due to amantadine's dopaminergic and adrenergic activity, and to a lesser extent, its activity as an anticholinergic. CNS side effects include nervousness, anxiety, agitation, insomnia, difficulty in concentrating, and exacerbations of pre-existing seizure disorders and psychiatric symptoms in patients with schizophrenia or Parkinson's disease. The usefulness of amantadine as an anti-parkinsonian drug is somewhat limited by the need to screen patients for a history of seizures and psychiatric symptoms.

Rare cases of severe skin rashes such as Stevens Johnson Syndrome^[14] and suicidal ideation in patients treated with amantadine have also been reported.^[15][16]

Livedo reticularis is a possible side effect of amantadine use for Parkinson's disease.^[17]